Tuesday, August 21, 2018

Bioinformatics Aids in Knowing the Intrinsically Disordered Proteins


Revolutionary changes in IT sector helps to build the best alternatives or options in every sector, especially in healthcare. Bioinformatics is also the outcome of technological development in the field of biology. We all are aware that bioinformatics has wide applications. By taking the advantage of bioinformatics, the scientist revealed the information about the intrinsically disordered proteins.
Proteins are the complex molecules made up of amino acids and act as the building block in every living organism. The proteins are involved in the process of growth and development. Also, it interferes with the metabolic processes carried out at the cellular level and creates the disease conditions. Apart from all, proteins work as an antibody which triggers many viruses and bacteria. Enzymes are also proteins and hence, participate in many chemical reactions and are involved in the process of copying DNA.
Scientists had worked a lot on the proteins and had sequenced 85 million unique proteins, structured and unstructured alike, but still, fails to predict functions of most of the proteins. For this, they need more advanced computer software to predict the functions of the newly discovered proteins.
Major Contributions
Lukasz Kurgan, the scientist from Virginia Commonwealth University, has developed a few bioinformatics software programs to support biological experts in improving knowledge about the functions of intrinsically disordered proteins. They are amorphous and flexible in nature and they do not have any specific three-dimensional structure. Read more..
Prediction of Unknown Functions of Known Structures
At the time of discovery of IDP, some people said that IDPs are just noise in the protein structures. But right now, scientists have obtained a lot of structural and functional knowledge of many proteins. It is a difficult task for them to know the functions of proteins which are totally or partly disordered. 

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